Table 1.
Baseline demographic characteristics of individuals participating in the selenium rrial by baseline adenoma status (n = 256).
| Non-Advanced | Advanced | p-Value | |
|---|---|---|---|
| n = 130 | n = 126 | ||
| Age (years) a | 63.3 (8.7) | 61.6 (8.3) | 0.12 |
| Sex b | 0.15 | ||
| Female | 48 (36.9%) | 36 (28.6%) | |
| Male | 82 (63.1%) | 90 (71.4%) | |
| Highest level of education b | 0.94 | ||
| High School or less | 25 (19.2%) | 22 (17.5%) | |
| Some College | 37 (28.5%) | 40 (31.7%) | |
| Bachelor’s Degree | 30 (23.1%) | 29 (23.0%) | |
| Graduate or Professional Degree | 38 (29.2%) | 35 (27.8%) | |
| Baseline Body Mass Index (kg/m2) a | 28.8 (5.2) | 28.7 (4.4) | 0.78 |
| Smoke cigarettes (≥100) b | 0.30 | ||
| Current | 8 (6.3%) | 13 (10.7%) | |
| Never | 58 (45.7%) | 46 (38.0%) | |
| Past | 61 (48.0%) | 62 (51.2%) | |
| Routine NSAID use b | 6 (4.6%) | 4 (3.2%) | 0.55 |
| Routine Aspirin use b | 60 (46.2%) | 49 (38.9%) | 0.24 |
| CRC in a first-degree relative b | 0.18 | ||
| None | 96 (76.8%) | 102 (83.6%) | |
| One or more | 29 (23.2%) | 20 (16.4%) | |
| History of polyps b | 49 (38.6%) | 39 (31.2%) | 0.22 |
| History of cancer b,d | 8 (6.2%) | 5 (4.0%) | 0.43 |
| Randomization c | 0.62 | ||
| Placebo | 69 (53.1%) | 62 (49.2%) | |
| Selenium | 61 (46.9%) | 64 (50.8%) | |
| Serum Selenium Concentration (ng/mL) a | 140.0 (26.2) | 132.5 (22.3) | 0.014 |
| Dietary Omega 6 (mg/day) a | 14.9 (9.1) | 13.6 (9.9) | 0.28 |
| Dietary Omega 3 (mg/day) a | 1.5 (0.7) | 1.3 (0.7) | 0.16 |
| Dietary Omega6/Omega3 Ratio) a | 9.9 (1.8) | 9.9 (2.4) | 0.97 |
Data are presented as mean (SD) or median (IQR) for continuous measures, and n (%) for categorical measures. a Two sample t-test; b Pearson’s chi-squared; c Fisher’s exact; d Excluding non-melanoma skin cancer; CRC: colorectal cancer; NSAIDs: Non-steroidal anti-inflammatory drugs.