. 2021 Nov 9;11(11):1167. doi: 10.3390/jpm11111167

Table 2.

Characteristics of the studies included in the review.

				Experimental Group								Control Group					Outcomes
				Sample Characteristics				Intervention Characteristics				Sample Characteristics					Outcomes
Authorship and Date	Country	K	N	N_e	Age	BMI	Evol. Years	Type	Weeks	Ses/Week	Min	N_c	Age	BMI	Evol. Years	Type Control	Variable	Test	Follow-Up
Collado-Mateo, D. et al., 2017a [62]	Spain	6	76	41	52.52	25.79	9.6	ni VRBT	8	2	60	35	52.47	27.75	11.02	NI	FMS Impact	FIQ	Inm. Effect
																	Quality of Life	EuroQol-5D
																	Fatigue	FIQ-Fatigue
																	Pain	FIQ-Pain
																	Anx/Dep	VAS
Collado-Mateo, D. et al., 2017b [64]	Spain	1	76	41	52.43	25.79	10.36	ni VRBT	8	2	60	35	52.58	27.75	12.48	NI	Dynamic Balance	TGUGT	Inm. Effect
García-Palacios, A. et al., 2015 [65]	Spain	4	59	30	50.48	NR	9.32	ni VRBT	3	2	60	29	50.48	NR	9.32	NI	FMS Impact	FIQ	Inm. Effect
																	Quality of Life	QLI-SP
																	Pain	BPI
																	Depression	BDI-II
Gulsen, C. et al., 2020 [66]	Turkey	5	16	8	46.5	26.81	4	iVRBT + CTBTE	8	2	80	8	38.5	22.85	4	CTBTE	FMS Impact	FIQ	Inm. Effect
																	Pain	VAS
																	Fatigue	FSS
																	Aerobic capacity	6-MWT
																	Quality of Life	SF-36
León-Llamas, J.L. et al., 2020 [67]	Spain	1/ QS	50	25	54	27	8.5	ni VRBT	24	2	60	25	53	28.5	11	NI	Aerobic capacity	PVO₂	Inm. Effect
Martín-Martínez, J.P. et al., 2019 [68]	Spain	1	55	28	54.04	27.36	19.2	ni VRBT	24	2	60	27	53.41	28.84	16.76	NI	Dynamic Balance	TGUGT	Inm. Effect
Polat, M. et al., 2021 [69]	Turkey	7	40	20	42.6	26.6	1.5	ni VRBT + CTBTE	8	3	35	20	47	27.9	1.4	CTBTE	FMS Impact	FIQ	Inm. Effect
																	Aerobic capacity	6-MWT
																	Pain	VAS
																	Fatigue	FSS
																	Quality of Life	EQ-5D-5L
																	Anx/Dep	HADS-A/-D
Silva de Carvalho, M. et al., 2020 [61]	Brasil	4	21	11	55.64	30.28	9.91	ni VRBT	7	3	60	10	47.7	26.09	14.65	ST	FMS Impact	FIQ	Inm. Effect
																	Aerobic capacity	6-MWT
																	Fatigue	FIQ-Fatigue
																	Pain	FIQ-Pain
Villafaina, S. et al., 2019a [63]	Spain	2	55	28	54.04	27.36	19.2	ni VRBT	24	2	60	27	53.41	28.84	16.74	NI	Pain	VAS	Inm. Effect
Villafaina, S. et al., 2019a [63]	Spain	2	55	28	54.04	27.36	19.2	ni VRBT	24	2	60	27	53.41	28.84	16.74	NI	Quality of Life	EQ-5D-5L	Inm. Effect
Villafaina, S. et al., 2019b [70]	Spain	3	37	22	54.27	27.1	NR	ni VRBT	24	2	60	15	53.44	28.19	NR	NI	FMS Impact	FIQ	Inm. Effect
																	Dynamic Balance	TGUGT
																	Aerobic capacity	6-MWT
Villafaina, S. et al., 2019c [71]	Spain	QS	50	25	52	NR	16	ni VRBT	24	2	60	25	54	NR	16	NI	Brain Dynamics	EEG Signals	Inm. Effect

Abbreviations: K, Number of comparisons provided; N, total sample size; Ne, experimental group sample size; BMI, body mass index; Evol, evolution; Ses, sSessions; Min, minutes; Nc, control group sample size; niVRBT, non-immersive virtual reality; iVR, immersive virtual reality; CTBTEM, conventional therapy based virtual training; ST, stretching exercise; FMS, fibromyalgia syndrome; FIQ, Fibromyalgia Impact Questionnaire; Anx, anxiety; Dep, depression; VAS, Visual Analogue Scale; TGUGT, Timed Get Up and Go Test; QLI-SP, Quality of Life Index; BPI, Brief Pain Inventory; BDI-II, Beck Depression Inventory II; FSS, Fatigue Severity Scale; EQ-5D-5L, The Euro Quality of Life Five Dimensions; HADS, Hospital Anxiety and Depression Scale-Anxiety Dimension; HADS-D, Hospital Anxiety and Depression Scale-Depression Dimension; EEG Signals, electroencephalographic signals.