Table 4.
Association between inflammatory biomarkers and sarcopenic obesity in older adults with chronic comorbidities, NHANES 1999-2006 (n = 2483).
| Variables | No. Sarcopenic Obesity/ Overall |
Prevalence (%) and 95% CI | cOR and 95% CI (n = 2483) |
aOR and 95% CI † (n = 2483) |
aOR and 95% CI § (n = 2483) |
|---|---|---|---|---|---|
| CRP (mg/L) | |||||
| <1.2 | 35/599 | 5.8 (4.2, 8.0) | REF | REF | REF |
| 1.2–2.5 | 53/636 | 8.3 (6.4, 10.8) | 1.46 (0.94, 2.27) | 1.43 (0.91, 2.26) | 1.37 (0.72, 2.61) |
| 2.6–5.2 | 52/619 | 8.4 (6.5, 10.9) | 1.28 (0.95, 2.30) | 1.44 (0.91, 2.28) | 1.30 (0.68, 2.48) |
| ≥5.3 | 50/629 | 7.9 (6.0, 10.3) | 1.39 (0.89, 2.17) | 1.46 (0.92, 2.33) | 1.61 (0.86, 3.03) |
| p-trend = 0.19 | p-trend = 0.15 | p-trend = 0.19 | |||
| SII (×109 cells/L) | |||||
| <365.7 | 31/620 | 5.0 (3.5, 7.0) | REF | REF | REF |
| 365.7–503.6 | 33/623 | 5.3 (3.8, 7.4) | 1.06 (0.64 1.76) | 0.97 (0.57, 1.62) | 0.99 (0.52, 1.85) |
| 503.7–704.0 | 57/619 | 9.2 (7.1, 11.8) | 1.92 (1.23, 3.03) | 1.58 (0.99, 2.54) | 1.34 (0.71, 2.52) |
| ≥704.1 | 69/621 | 11.1 (8.9, 13.8) | 2.38 (1.53, 3.69) | 1.94 (1.23, 3.07) | 2.32 (1.32, 4.05) |
| p-trend < 0.01 | p-trend < 0.01 | p-trend < 0.01 |
Abbreviations—aOR: adjusted odds ratio; CI: confidence interval; cOR: crude odds ratio; REF: reference; CRP: C-reactive protein; SII: systemic immune-inflammation index. † The model adjusted for age; sex; race; education; marital status; smoking; physical activity; alcohol use; dietary intake of carbohydrates, total fat, protein, and energy; and multimorbidity. § The model adjusted for the same set of covariates, but corrected for the NHANES sampling weights.