Table 5.
Subgroup analysis for association between inflammatory biomarkers and sarcopenic obesity, NHANES 1999-2006 (n = 2483).
| Variables | CRP (mg/L) | p-Trend | SII (×109 cells/L) | p-Trend | ||||
|---|---|---|---|---|---|---|---|---|
| aOR and 95% CI | aOR and 95% CI | |||||||
| 1.2–2.5 vs. <1.2 | 2.6–5.2 vs. <1.2 | ≥ 5.3 vs. <1.2 | 365.7–503.6 vs. <365.7 |
503.7–704.0 vs. <365.7 |
≥704.1 vs. <365.7 |
|||
| Age (year) | ||||||||
| <70 (n = 1319) | 1.15 (0.51, 2.61) | 1.31 (0.60, 2.88) | 1.43 (0.65, 3.13) | 0.34 | 0.59 (0.24, 1.44) | 2.01 (0.95,4.25) | 1.46 (0.66, 3.20) | 0.06 |
| ≥70(n = 1164) | 1.62 (0.93, 2.83) | 1.48 (0.84, 2.62) | 1.36 (0.75, 2.45) | 0.43 | 1.29 (0.67, 2.48) | 1.46 (0.79, 2.69) | 2.41 (1.35, 4.30) | <0.01 |
| p-interaction = 0.78 | p-interaction = 0.08 | |||||||
| Sex | ||||||||
| Female (n = 1292) | 1.66 (0.85, 3.27) | 1.37 (0.70, 2.69) | 1.27 (0.65, 2.49) | 0.78 | 0.92 (0.43, 1.96) | 1.85 (0.94, 3.61) | 2.45 (1.27, 4.74) | <0.01 |
| Male (n = 1191) | 1.30 (0.69, 2.45) | 1.58 (0.82, 3.03) | 1.62 (0.82, 3.18) | 0.13 | 1.01 (0.49, 2.11) | 1.46 (0.73, 2.92) | 1.78 (0.92, 3.44) | 0.04 |
| p-interaction = 0.69 | p-interaction = 0.96 | |||||||
| Multimorbidity | ||||||||
| No (n = 894) | 0.96 (0.38, 2.39) | 1.63 (0.71, 3.74) | 1.30 (0.53, 3.20) | 0.34 | 1.52 (0.56, 4.08) | 2.58 (0.98, 6.78) | 2.54 (0.97, 6.63) | 0.03 |
| Yes (n = 1589) | 1.68 (0.97, 2.88) | 1.52 (0.86, 2.68) | 1.61 (0.91, 2.83) | 0.18 | 0.80 (0.43, 1.51) | 1.34 (0.77, 2.32) | 1.83 (1.07, 3.11) | <0.01 |
| p-interaction = 0.67 | p-interaction = 0.76 | |||||||
Abbreviations—aOR: adjusted odds ratio; CI: confidence interval; CRP: C-reactive protein; SII: systemic immune-inflammation index. The model was adjusted for the same set of covariates as the primary model, except for those used for stratification.