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Structure of SARS-CoV-2 and diagnostic targets: SARS-CoV-2 structure has two components: viral genome (RNA) and viral proteins. Tests based on the detection of nucleic acids (RT-qPCR, RT-LAMP, CRISPR-Cas-based, NGS) target different regions of the viral RNA. Antigen tests aim at the detection of viral proteins such as spike protein (S). Serological tests detect host antibodies produced in response to SARS-COV-2 infection.
