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. 2021 Nov 12;22(22):12253. doi: 10.3390/ijms222212253

Figure 4.

Figure 4

The role of DAPs in ciliogenesis. (A). CEP83 recruits E3 ligase and phosphorylates TTBK2 to remove the CP110–CEP97 complex and induce MPP9 degradation. (B). CEP164 has three roles: (1) the formation of the CEP164–Cby complex to recruit TTBK2; (2) the recruitment of EDH1 to enhance PCV formation; and (3) the interaction with Rabin8 to activate Rab8. (C). LRRC45 and CEP89 organize centriolar satellites. CEP89 plays a direct role in EDH1 recruitment. (D) FBF1 regulates the lateral diffusion of the IFT complex. Image was created by BioRender.