ABR |
ABR Activator of Rho GEF and GTPase |
ADCY1 |
Adenylate Cyclase 1 |
ADCY6 |
Adenylate Cyclase 6 |
AKT |
Protein kinase B |
ALK |
Anaplastic Lymphoma Kinase |
AT1 |
Angiotensin II type 1 |
cAMP |
cyclic adenosine -3’,5’-monophosphate |
CCL2 |
C-C Motif Chemokine Ligand 2 |
CCNE1 |
cyclin E |
CDK4 |
Cyclin-Dependent Kinase 4 |
CDKN1A |
Cyclin-Dependent Kinase Inhibitor 1A |
CTNNB1 |
catenin beta 1 |
CDR1as |
Circular RNA CDR1as |
c-MET |
hepatocyte growth factor receptor |
DUSP4 |
Dual Specificity Phosphatase 4 |
EGF |
Epidermal Growth Factor |
EGFR |
Epidermal Growth Factor Receptor |
eIF4e |
Eukaryotic translation initiation factor 4E |
EMT |
Epithelial-Mesenchymal Transition |
ERF |
Ets2 transcriptional repression factor |
ERK1/2 |
Extracellular Signal-Regulated Kinase 1/2 |
GABBR1 |
Gamma-Aminobutyric Acid Type B Receptor Subunit 1 |
GIPR |
Gastric Inhibitory Polypeptide Receptor |
GPR124 |
G protein-coupled receptor124 |
GRB2 |
growth factor receptor-bound protein 2 |
HIF-1α |
Hypoxia Inducible Factor 1 Subunit Alpha |
HuR |
Human Antigen R |
IC50 |
Inhibit Cellular Proliferation by 50% |
IGF-1R |
Insulin-like Growth Factor Receptor-1 |
IL-6 |
Interleukin-6 |
JAK1 |
Janus kinase 1 |
KRAS |
Kirsten Rat Sarcoma Viral Oncogene Homolog |
LADC |
Lung Adenocarcinoma |
3LL |
Lewis lung cancer |
LSCC |
Lung Squamous Carcinoma |
MAGI2 |
Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 2 |
MAPK (MEK) |
Mitogen-Activated Protein Kinase |
mTOR |
mammalian/mechanistic target of rapamycin. |
MUC4 |
Mucin 4 |
NF-kB |
Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells |
NSCLC |
Non-Small Cell Lung Cancer |
NRSF |
Neuron-Restricted Silencing Factor |
NUDT-1 |
Nucleoside X-type Motif-1 |
PDE4B |
Phosphodiesterase 4b |
PDE4C |
Phosphodiesterase 4c |
PDGFRa |
platelet-derived growth factor receptor Alpha |
PI3K |
Phosphatidylinositol 3-kinase |
PIK3CD |
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta |
PIK3R2 |
phosphoinositide-3-kinase regulatory subunit 2 |
PLCG1 |
phospholipase C gamma 1 |
PTEN |
phosphatase tensin homologue |
PTK2 |
protein tyrosine kinase 2 |
SCLC |
Small Cell Lung Cancer |
STAT |
Signal Transducer and Activator of Transcription |
RAAS |
Renin-Angiotensin-Aldosterone System |
Ras |
Rat Sarcoma |
Raf |
Rapidly Accelerated Fibrosarcoma |
RAF-1 |
Rapidly Accelerated Fibrosarcoma homolog-1 |
RHOA |
Transforming protein RhoA |
Ron |
a protein tyrosine kinase related to c-MET |
RTK |
Receptor Tyrosine Kinase |
TCA |
Tricarboxylic Acid Cycle |
TGFβ |
Transforming Growth Factor Beta |
TKIs |
Tyrosine Kinase Inhibitors |
TNFAIP3 |
Tumor necrosis factor, alpha-induced protein 3 or A20 |
TNM |
Tumor, nodes, and metastasis |
TRPM2 |
Transient receptor potential cation channel, subfamily M, member 2 |
VEGFA |
Vascular endothelial growth factor-A |
VHL |
Von Hippel–Lindau disease |
ZEB1 |
zinc finger E-box binding homeobox 1 |