Skip to main content
. 2021 Nov 19;22(22):12496. doi: 10.3390/ijms222212496
ABR ABR Activator of Rho GEF and GTPase
ADCY1 Adenylate Cyclase 1
ADCY6 Adenylate Cyclase 6
AKT Protein kinase B
ALK Anaplastic Lymphoma Kinase
AT1 Angiotensin II type 1
cAMP cyclic adenosine -3’,5’-monophosphate
CCL2 C-C Motif Chemokine Ligand 2
CCNE1 cyclin E
CDK4 Cyclin-Dependent Kinase 4
CDKN1A Cyclin-Dependent Kinase Inhibitor 1A
CTNNB1 catenin beta 1
CDR1as Circular RNA CDR1as
c-MET hepatocyte growth factor receptor
DUSP4 Dual Specificity Phosphatase 4
EGF Epidermal Growth Factor
EGFR Epidermal Growth Factor Receptor
eIF4e Eukaryotic translation initiation factor 4E
EMT Epithelial-Mesenchymal Transition
ERF Ets2 transcriptional repression factor
ERK1/2 Extracellular Signal-Regulated Kinase 1/2
GABBR1 Gamma-Aminobutyric Acid Type B Receptor Subunit 1
GIPR Gastric Inhibitory Polypeptide Receptor
GPR124 G protein-coupled receptor124
GRB2 growth factor receptor-bound protein 2
HIF-1α Hypoxia Inducible Factor 1 Subunit Alpha
HuR Human Antigen R
IC50 Inhibit Cellular Proliferation by 50%
IGF-1R Insulin-like Growth Factor Receptor-1
IL-6 Interleukin-6
JAK1 Janus kinase 1
KRAS Kirsten Rat Sarcoma Viral Oncogene Homolog
LADC Lung Adenocarcinoma
3LL Lewis lung cancer
LSCC Lung Squamous Carcinoma
MAGI2 Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 2
MAPK (MEK) Mitogen-Activated Protein Kinase
mTOR mammalian/mechanistic target of rapamycin.
MUC4 Mucin 4
NF-kB Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells
NSCLC Non-Small Cell Lung Cancer
NRSF Neuron-Restricted Silencing Factor
NUDT-1 Nucleoside X-type Motif-1
PDE4B Phosphodiesterase 4b
PDE4C Phosphodiesterase 4c
PDGFRa platelet-derived growth factor receptor Alpha
PI3K Phosphatidylinositol 3-kinase
PIK3CD Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
PLCG1 phospholipase C gamma 1
PTEN phosphatase tensin homologue
PTK2 protein tyrosine kinase 2
SCLC Small Cell Lung Cancer
STAT Signal Transducer and Activator of Transcription
RAAS Renin-Angiotensin-Aldosterone System
Ras Rat Sarcoma
Raf Rapidly Accelerated Fibrosarcoma
RAF-1 Rapidly Accelerated Fibrosarcoma homolog-1
RHOA Transforming protein RhoA
Ron a protein tyrosine kinase related to c-MET
RTK Receptor Tyrosine Kinase
TCA Tricarboxylic Acid Cycle
TGFβ Transforming Growth Factor Beta
TKIs Tyrosine Kinase Inhibitors
TNFAIP3 Tumor necrosis factor, alpha-induced protein 3 or A20
TNM Tumor, nodes, and metastasis
TRPM2 Transient receptor potential cation channel, subfamily M, member 2
VEGFA Vascular endothelial growth factor-A
VHL Von Hippel–Lindau disease
ZEB1 zinc finger E-box binding homeobox 1