Table 7.
Comparison of the calculated theoretical MICs (theoMICs) for components of DC&RCP and P-128CP to the actual MIC levels of components required for inhibition of 63 Staphylococcus aureus strains isolated from feces to 101 S. aureus strains from swine mandibular lymph node tissue and commercial pork sausage meat in μg/mL. MIC = minimum inhibition concentration.
| DC&R Component MICs—Feces Strains | DC&R Component MICs—Tissue & Sausage | ||||
|---|---|---|---|---|---|
| Component | Calculated theoMICs | Actual MICs from Table 3 * | Component | Calculated theoMICs | Actual MICs from Table 4 † |
| theoBACsDC&R | 0.25 (9.6%) ‡ | 0.125 (0.5%) ‡ | theoBACsDC&R | 0.25 (2.0%) ‡ | 0.25 (1.0%) ‡ |
| 0.5 (46.0%) | 0.25 (3.7%) | 0.5 (25.7%) | 0.5 (31.0%) | ||
| 1.0 (44.4%) | 0.5 (37.0%) | 1.0 (52.5%) | 1.0 (25.8%) | ||
| 1.0 (24.3%) | 2.0 (5.9%) | 2.0 (33.3) | |||
| 2.0 (33.3%) | 4.0 (13.9%) | 4.0 (3.3%) | |||
| 4.0 (1.1%) | 8.0 (5.6%) | ||||
| theoFormDC&R | 0.19 (9.5%) ‡ | 16.0 (1.6%) ‡ | theoFormDC&R | 0.19 (2.0%) ‡ | 32.0 (2.0%) ‡ |
| 0.37 (46.0%) | 32.0 (28.6%) | 0.37 (25.7%) | 64.0 (98.0%) | ||
| 0.74 (44.4%) | 64.0 (68.2%) | 0.74 (52.5%) | |||
| 128.0 (1.6%) | 1.49 (5.9%) | ||||
| 2.97 (13.9%) | |||||
| theoTHNDC&R | 1.56 (9.5%) ‡ | 128.0 (1.6%) ‡ | theoTHNDC&R | 1.56 (2.0%) ‡ | 128.0 (2.0%) ‡ |
| 3.13 (46.0%) | 256.0 (95.2%) | 3.13 (25.7%) | 256.0 (77.2%) | ||
| 6.25 (44.4%) | 512.0 (3.2%) | 6.25 (52.5%) | 512.0 (19.8%) | ||
| 12.51 (5.9%) | 1024.0 (1.0%) | ||||
| 25.0 (13.9%) | |||||
| P-128 Component MICs—Feces Strains | P-128 Component MICs—Tissue & Sausage Strains | ||||
| theoBACsP-128 | 0.1 (4.8%) ‡ | 0.125 (0.5%) ‡ | theoBACsP-128 | 0.1 (1.0%) ‡ | 0.25 (1.0%) ‡ |
| 0.2 (85.7%) | 0.25 (3.7%) | 0.2 (63.4%) | 0.5 (31.0%) | ||
| 0.4 (9.5%) | 0.5 (37.0%) | 0.4 (22.8%) | 1.0 (25.7%) | ||
| 1.0 (24.3%) | 0.8 (12.9%) | 2.0 (33.3%) | |||
| 2.0 (33.3%) | 4.0 (3.3%) | ||||
| 4.0 (1.1%) | 8.0 (5.6%) | ||||
| theoC10ACP-128 | 0.15 (4.8%) ‡ | 0.125 (3.2%) ‡ | theoC10ACP-128 | 0.15 (1.0%) ‡ | 0.25 (20.8%) ‡ |
| 0.3 (85.7%) | 0.25 (30.1%) | 0.3 (63.4%) | 0.5 (58.4%) | ||
| 0.6 (9.5%) | 0.5 (65.1%) | 0.6 (22.8%) | 1.0 (12.9%) | ||
| 1.0 (1.6%) | 1.2 (12.9%) | 2.0 (7.9%) | |||
* Component MICs obtained from Table 4 for the BACs, (C12BAC, C14BAC, and C16BAC), Form (formaldehyde), THN (tris(hydroxylmethyl)nitromethane), and C10AC (didecyldimethylammonium chloride) against S. aureus strains from feces. † Component MICs obtained from Table 5 for the BACs, (C12BAC, C14BAC, and C16BAC), formaldehyde, THN (tris(hydroxylmethyl)nitromethane), and C10AC (didecyldimethylammonium chloride) against S. aureus strains from the MLT and PSM. ‡ Percentage of strains at the indicated MIC.