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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Nat Med. 2021 Oct 18;27(11):1921–1927. doi: 10.1038/s41591-021-01521-4

Extended Data Fig. 2. Association of between the types of mCA and hematologic malignancies.

Extended Data Fig. 2

All three categories of mCAs copy loss, copy gain, and copy neutral loss-of-heterozygosity are associated with the risk of a) myeloid malignancies, and b) lymphoid malignancies. (a-b) Data are presented as hazard ratio and 95% confidence intervals, computed by Cox proportional hazards model adjusting for age, sex, smoking, genetic ethnic ancestry, and genetic principal components 1–5. LOH, loss-of-heterozygosity; del, copy loss (deletion); gain, copy gain; HR, hazard ratio; CI, confidence interval.