Fig. 1.

Repetitive behavior counts per 15 min period (mean ± standard error of the mean (SEM)) across the 12 -h dark cycle for Day 1 (1A) and Day 7 (1B), respectively. Upward light-colored arrows indicate time of drug or vehicle administration. Upward black arrows indicate times that non-repetitive behaviors were sampled. Fig. 1C: Total repetitive behavior counts over the 12 -h dark cycle for days 1 and 7. Drug cocktail-treated mice exhibited significantly less repetitive behavior on days 1 and 7 during the seven days of repeated administration (mean ± SEM; *** p < 0.001 for Bonferroni post-tests).