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. 2021 Nov 13;10(11):3162. doi: 10.3390/cells10113162

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Plasticity in the dLGN. (A) Structural plasticity. Refinement, synapse elimination and synapse strengthening at rodent retino-geniculate inputs during postnatal development. Synaptic currents evoked by increasing stimulus intensity before eye opening (left) and in the adult (right). Note the multiple and small synaptic responses in immature dLGN neurons and the all-or-none and large response in mature dLGN neurons. (B) Hebbian synaptic plasticity at retino-geniculate synapses induced by pairing presynaptic stimulation with postsynaptic firing with synchronous (left) or asynchronous (right) relation. Adapted from [62]. (C) Homeostatic plasticity at cortico-geniculate synapses. MD induces an up-regulation of synaptic transmission. Adapted from [63]. NR, normal rearing.