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. 2021 Nov 16;26(22):6897. doi: 10.3390/molecules26226897

Figure 6.

Figure 6

CB1 receptor coupling to Gαi/o proteins in control and 10 mM MβCD pretreated synaptosomes from frontal cortical tissue of Glu-CB1-RS and GABA-CB1-RS mice. (A,B) Bar graph of 10 µM CP 55,940 and 10 µM WIN 55,212-2-stimulated maximal [35S]GTPγS binding. (C,D) Concentration–response curves for the CP 55,940-stimulated [35S]GTPγS binding. Concentration–response curves were constructed using mean values ± SEM from triplicate data points of three independent experiments. Emax values are expressed as % specific [35S]GTPγS bound of basal.