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. 2021 Nov 19;22(22):12500. doi: 10.3390/ijms222212500

Figure 2.

Figure 2

Atorvastatin protects RGCs from chronic OHT-induced cell death. (a) The retinas were either stained with H&E or processed by immunohistochemistry for Brn3a or cleaved caspase-3. The number of cells (b), number of Brn3a+ cells (c), and cleaved caspase-3+ cells (d) in the GCL were quantified. Atorvastatin injection protected RGCs from chronic OHT-induced injury. GCL: Ganglion cell layer, IPL: inner plexiform layer, INL: inner nuclear layer, OPL: outer plexiform layer, ONL: outer nuclear layer, H&E: hematoxylin and eosin, OHT: ocular hypertension, RGCs: retinal ganglion cells; * p < 0.05, † p < 0.01; n = 5 for each group.