Figure 6.
Comparison of two different LSDV vector backbones with the same BEFV gene inserts. Rabbits (n = 5 per group) were given three inoculations, 28 days apart, of either LSDV(∆SOD)BEFV-Gb-M or LSDV(SODis)BEFV-Gb-M, intramuscularly, at a dose of 106 ffu per rabbit. Blood was taken 14 days after the final inoculation and serum was tested for neutralization of BEFV and LSDV. Neutralization titres are expressed as the reciprocal of the dilution required to neutralize virus in 50% or more of wells of cells infected with BEFV (blue) or LSDV (orange), respectively.