Figure 3.

Effect of different concentrations of dietary sodium on the production of cytokines by splenocytes. Splenocytes were isolated from the spleens after OVA challenge and incubated in culture medium containing fetal bovine serum (FBS) and OVA for 1 to 3 days. Interleukin (IL)-4 (a), IL-10 (b), and interferon- γ (IFN-γ) (c) were measured by sandwich ELISA. Data are expressed as box-and-whisker plots with individual data points. The boxes represent the inner quartiles value range with the median indicated as black line. The whiskers represent minimum to maximum interval. * p < 0.05 and ** p < 0.01. High-salt diet: HSD, Low-salt diet: LSD, Control diet: CTRL.