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. 2021 Oct 29;11(11):1118. doi: 10.3390/jpm11111118

Table 1.

Correlation between intestinally generated uremic toxins and transit time of patients with CKD.

Correlation to BSS All CKD Stages
(n = 111)
CKD Stage 1–2
(n = 37)
CKD Stage 3
(n = 44)
CKD Stage 4–5
(n = 33)
Uremic Toxin rs p-Value rs p-Value rs p-Value rs p-Value
Indoxyl sulfate −0.173 ns −0.130 ns −0.054 ns −0.223 ns
Indole-3-acetic acid −0.150 ns −0.035 ns −0.041 ns −0.206 ns
Hippuric acid −0.343 <0.001 −0.366 0.036 −0.153 ns −0.318 ns
p-Cresyl sulfate −0.287 0.003 −0.335 ns −0.134 ns −0.443 0.012
p-Cresyl glucuronide −0.175 ns −0.105 ns −0.116 ns −0.340 ns

BSS: Bristol stool scale which is used to assess transit time (slow transit = low BSS); CKD: chronic kidney disease; rs: Spearman’s correlation coefficient; bold: significant; ns: not significant.