Table 2.
Application of MC in ocular drug delivery.
| Cellulosic Polymer | Drug Used | Application of Polymer | Effect on Drug Property | Ref |
|---|---|---|---|---|
| MC | Betaxolol hydrochloride | Sustain release upto 43% in 4 h | Enhanced AUC and MRT that is 47.10 ± 3.38 µL·h·g−1 and 5.17 ± 1.28 h compared to commercial preparation one 28.95 ± 4.12 µL·h·g−1 and 2.20 ± 0.06 h | [132] |
| Sunitinib malate | Shear thinning agent, Zero shear prior injection | Enhanced injectability of MP, high retention of MPs after injection, reduced injection related inflammation, overall extended release | [133] | |
| Tranilast | Prolonged residence time | Enhanced efficacy of inflammation preventive effect of TL-NPs containing 0.5 or 1.5% MC, TNF-α and NO level was 50 pg/mg protein and 20 nM that is lowest in TL-MMC | [134] | |
| Pilocarpine nitrate | Bio-adhesion | Enhanced bioavailability due to bioadhesive nature of polymer | [135] |