Table 4.

Summarized information about mycotoxins and their relationship to claudins in colon cancer cell lines. * only markedly affected, but distribution was disturbed, ↓ lower value/expression, AFM1—aflatoxin M1, ZEA—zearalenon, OTA—ochratoxin A, AFB1—aflatoxin B1.

Mycotoxin	Cell Line	TEER Values	Targeted Claudin	References
Aflatoxin B1	Caco-2	↓	CLDN3 ↓	[213]
Ochratoxin A	Caco-2, HT-29-DR	↓	CLDN3, CLDN4 ↓	[213,221,222]
Patulin	Caco-2	↓	CLDN1, CLDN3, CLDN4) ↓ *	[204,209,213]
T-2 toxin	Caco-2	↓	CLDN3, CLDN4 ↓	[213]
Fumonisin B1	Caco-2	↓	CLDN3, CLDN4 ↓	[213]
Deoxynivalenol	Caco-2, T84, HT-29-DR	↓	CLDN4 ↓	[188,212]
AFM1 + ZEA + OTA (combination)	Caco-2	↓	CLDN3, CLDN4	[215]
AFM1 + OTA	Caco-2	↓	CLDN3, CLDN4	[217]
AFM1 + AFB1	Caco-2	↓	CLDN1	[153]