Table 2.
Hematological measurements in patients with recurrent and non-recurrent hepatocellular carcinoma at pre-resection and post-resection 1.
| Parameters | Recurrence (n = 48) | Non-Recurrence (n = 44) | ||||||
|---|---|---|---|---|---|---|---|---|
| Pre-Resection | Post-Resection | p Value 2 | Δ(Post—Pre-Resection) | Pre-Resection | Post-Resection | p Value 2 | Δ(Post—Pre-Resection) | |
| ALT (U/L) | 64.4 ± 8.2 (43.5) |
54.2 ± 7.2 (39.5) |
0.12 | −10.3 ± 8.0 (−3.0) |
76.4 ± 15.6 (37.0) |
44.2 ± 4.7 (35.5) |
0.10 | −33.9 ± 16.5 (−2.0) |
| AST (U/L) | 63.0 ± 8.7 (36.5) |
42.8 ± 5.6 (31.5) |
0.01 | −20.2 ± 9.0 (−5.5) |
77.5 ± 15.4 (37.0) |
37.3 ± 3.5 (30.0) |
0.003 | −42.9 ± 16.4 (−5.5) |
| α-fetoprotein (ng/mL) |
1240.1 ± 941.8 (19.1) |
34.1 ± 10.0 (9.8) |
<0.001 | −1205.3 ± 937.4 (−3.1) |
2562.8 ± 1504.8 (31.3) |
119.8 ± 67.0 # (5.7) |
<0.001 | −2652.5 ± 1594.0 (−21.8) |
| Total bilirubin (mg/dL) |
0.6 ± 0.04 (0.6) |
1.1 ± 0.3 3 (0.8) |
0.01 | 0.5 ± 0.3 (0.2) |
0.7 ± 0.1 (0.6) |
0.7 ± 0.1 4 (0.6) |
0.58 | 0.02 ±0.03 (0.0) |
| Albumin (g/dL) |
4.1 ± 0.1 (4.1) |
4.1 ± 0.1 3 (4.1) |
0.69 | −0.01 ± 0.8 (0.1) |
4.1 ± 0.1 (4.1) |
4.3 ± 0.04 # (4.3) |
0.004 | 0.2 ± 0.1 † (0.1) |
| hs-CRP (mg/dL) | 0.9 ± 0.3 (0.2) |
0.7 ± 0.1 (0.4) |
0.07 | −0.2 ± 0.3 (0.1) |
0.4 ± 0.1 (0.1) |
0.5 ± 0.2 (0.3) |
0.01 | 0.1 ± 0.2 (0.1) |
| BUN (mg/dL) |
14.3 ± 0.8 (13.0) |
16.1 ± 0.9 (15.0) |
0.01 | 1.7 ± 0.7 (2.0) |
14.6 ± 0.9 (13.5) |
16.1 ± 0.9 (15.0) |
0.49 | 0.6 ± 0.8 (0.5) |
1 Values are means ± standard error with median in parentheses. ALT, alanine aminotransferase; AST, aspartate aminotransferase; hs-CRP, high sensitivity C-reactive protein; BUN, blood urea nitrogen. 2 The comparison of value at pre-resection and at post-resection within group. 3 n = 24. 4 n = 33. # Values are significantly different from recurrence group at post-resection (p < 0.05). † Values are significantly different to the recurrence group in ∆(Post—Pre-resection) (p < 0.05).