Table 3.

Incidence rates and risk of type 2 diabetes in colectomy and non-colectomy patients without colorectal cancer.

Variables	Colectomy Cases			Non-Colectomy Controls			Compared with the Non-Colectomy Controls
	n = 642			n = 2568			Crude HR	Adjusted HR a
	Event	Person Years	IR	Event	Person Years	IR	(95% CI)	(95% CI)
Overall	65	3151	20.63	398	14254	27.92	0.74 (0.57–0.96) *	0.80 (0.61–1.04)
Age at baseline (years)
<40	5	778	6.43	30	3213	9.34	0.69 (0.27–1.77)	0.67 (0.26–1.72)
40–64	33	1396	23.63	149	6194	24.06	0.99 (0.68–1.44)	0.98 (0.67–1.44)
≥65	27	977	27.63	219	4847	45.18	0.62 (0.41–0.92) *	0.67 (0.45–1.00)
Sex
Female	31	1172	26.45	159	5806	27.38	0.96 (0.66–1.42)	1.11 (0.75–1.63)
Male	34	1980	17.18	239	8448	28.29	0.61 (0.42–0.87) **	0.62 (0.43–0.89) **
Baseline comorbidity
Hypertension	30	994	30.17	250	5011	49.89	0.61 (0.42–0.89) *	0.63 (0.43–0.93) *
Hyperlipidemia	15	483	31.03	90	2000	45.00	0.68 (0.39–1.17)	0.68 (0.39–1.19)
Cerebrovascular disease	5	354	14.11	93	1964	47.35	0.30 (0.12–0.73) **	0.32 (0.13–0.79) *
Heart disease	26	867	30.00	227	4647	48.85	0.62 (0.41–0.93) *	0.66 (0.44–0.99) *
Thyroid disease	3	161	18.59	11	680	16.17	1.16 (0.32–4.15)	1.11 (0.29–4.21)
COPD	14	532	26.33	116	2735	42.41	0.63 (0.36–1.09)	0.65 (0.37–1.14)
Renal disease	5	200	25.06	52	960	54.16	0.47 (0.19–1.17)	0.51 (0.20–1.31)
Liver disease	22	667	32.98	119	3428	34.71	0.97 (0.61–1.52)	1.03 (0.65–1.63)
Anemia	9	348	25.89	55	1810	30.39	0.87 (0.43–1.76)	0.89 (0.43–1.84)
Immune disorder	1	13	74.24	3	83	36.07	2.08 (0.21–20.12)	-

IR: incidence rate per 1000 person years; HR: hazard ratio; CI: confidence interval; COPD: chronic obstructive pulmonary disease. ^a Adjusted HR: adjusted for age and comorbidities in Cox proportional hazards regression. * p < 0.05; ** p < 0.01.