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A schematic diagram of MNP-mediated ICD, tumor antigen release, and DC maturation. (a) Synthesis of the ANP/HSP-Cas9 complex. (b) Photothermal activation of PD-L1 genome editing. (c) NIR laser-induced photothermal therapy triggers ICD and antigen presentation, thereby activating the T cells. Reproduced with permission from [20] published by John Wiley and Sons, 2021.
