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. 2021 Nov 9;11(11):1206. doi: 10.3390/life11111206

Table 2.

Sm and LV-EF in CAV and ACR.

CAV Grade ISHLT CAV1 n = 5 ISHLT CAV2 n = 4 ISHLT CAV3 n = 20
Pre CAV1 Change Pre CAV2 Change Pre CAV3 Change (CI) p value
Sm rad cm/s 10.7 9.9 −0.8 11.0 10.3 0.8 10.5 9.3 1.3 (0.23–2.43)
(±1.2) (±0.7) (±1.69) (±2.2) (±1.5) (±2.2) (±1.9) (±2.9) (±2.5) 0.017
Sm long cm/s 11.0 9.2 −1.8 10.8 10.8 0 10.6 9.5 1.4 (0.21–2.66)
(±1.4) (±0.7) (±1.3) (±2.2) (±2.2) (±2.5) (±2.2) (±2.6) (±2.8) 0.021
LV-EF % 60.0 56.0 −4.0 58.8 55.5 −3.75 56.9 52.1 4.8 (0.42–9.18)
(±3.2) (±11.6) (±8.6) (±4.1) (±3.5) (±1.1) (±6.7) (±12.0) (±10.0) 0.031
ACR grade ISHLT 1R n = 84 ISHLT 2R n = 13 ISHLT 3R n = 8
pre 1R change (CI)
p value
pre 2R change pre 3R change
Sm rad cm/s 11.3 9.6 −1.7 (1.32–2.08) 11.3 9.1 −1.9 11.4 9.4 −2.6
(±2.0) (±2.0) (±1.8) <0.001 (±1.7) (±2.4) (±2.3) (±2.1) (±2.1) (±3.0)
Sm long cm/s 11.8 10.0 −2.0 (1.66–2.34) 11.7 9.1 −2.3 11.9 9.1 −3.4
(±1.7) (±2.4) (±1.6) <0.001 (±1.8) (±2.9) (±2.4) (±1.8) (±1.8) (±1.9)
LV-EF % 62.6 57.9 −5.3 (3.85–6.75) 60.4 53.8 −7.1 65.0 54.4 −10.6
(±5.8) (±8.8) (±6.8) <0.001 (±4.0) (±12.7) (±16.2) (±3.5) (±14.5) (±13.3)

ACR, acute cellular rejection; CAV, cardiac allograft vasculopathy; CI, confidence interval; ISHLT, International Society for Heart and Lung Transplantation; long, longitudinal; LV-EF, left ventricular rejection fraction; rad radial; Sm, systolic wall motion peak velocity.