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Mechanisms of various experimental methods for induction of dry eye disease. LG, lacrimal gland; LGS, lacrimal gland secretion; HG, Harderian gland; MBG, Meibomian gland; ICES, Intelligently controlled environmental system; BAC, Benzalkonium chloride; NAC, N-acetylcysteine; MAPK, Mitogen-activated protein kinase; NFkB, Nuclear factor kappa B; IL-6, Interleukin 6; IL-1β, Interleukin-1beta; MMPs, Matrix metalloproteinases; VEGF, Vascular endothelial growth factor.
