Table 4.
Multiple Cox regression models predicting lung cancer mortality.
Model | Parameters | HR | 95% CI HR | p |
---|---|---|---|---|
I (for serum SOD1 concentration) | Serum SOD1 per 1 pg/mL | 1.005 | 1.002–1.008 | <0.001 |
Clinical stage IV vs. I | 3.22 | 1.61–6.44 | <0.001 | |
Clinical stage III vs. I | 3.25 | 1.53–6.90 | 0.002 | |
Clinical stage II vs. I | 0.61 | 0.22–1.72 | 0.350 | |
II (for serum SOD2 concentration) | Serum SOD2 per 1 ng/mL | 1.30 | 1.09–1.56 | 0.005 |
Clinical stage IV vs. I | 2.55 | 1.22–5.35 | 0.013 | |
Clinical stage III vs. I | 3.03 | 1.40–6.56 | 0.005 | |
Clinical stage II vs. I | 0.76 | 0.27–2.15 | 0.602 |
SOD1: superoxide dismutase 1; SOD2: superoxide dismutase 2; HR: hazard ratio; CI: confidence interval. Models I and II were adjusted using the following parameters: albumin (continuous), DM (yes/no), clinical stage (I/II/III/IV), platelet count (<150/150–400/>400 × 103 cells/µL), NLR (<2.67 vs. ≥2.67 arbitrary unit), ceruloplasmin (<0.266 vs. ≥0.266 g/L), CRP (≤10 vs. >10 mg/dL), and GPS (arbitrary unit).