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. 2021 Oct 26;12(11):1701. doi: 10.3390/genes12111701

Figure 4.

Figure 4

Circ_0092367 Serves as a MiR-1206 Sponge in PC Cells. (A) The subcellular location of circ_0092367 in PaCa-2 cells. (B) The complementary sequence between miR-1206 and circ_0092367 (CircInteractome). (C) MiR-1206 expression in PC tissues and adjacent normal tissues. (D) MiR-1206 expression in PC cells and normal cells. (E) Kaplan–Meier survival analysis of PC patients with lower versus higher miR-1206 expression. (F) MiR-1206 expression in PC cells transfected as indicated was investigated with qRT-PCR analysis. (G) PC cells were transfected with wild-type (WT) or mutant (MUT) circ_0092367, with miR-1206 mimic and miR-1206 inhibitor, and luciferase assays were performed. The experiments in (A,D,F,G) were repeated three times independently with similar results. *** p < 0.001.