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. 2021 Oct 26;12(11):1701. doi: 10.3390/genes12111701

Figure 7.

Figure 7

MiR-1206 Enhances PC Cell Invasion and Gemcitabine Resistance via Targeting ESRP1. (A) PC cells were transfected with either wild-type (WT) or mutant (MUT) ESRP1 3′-UTR, with miR-1206 mimic or miR-1206 inhibitor, and luciferase reporter assays were performed. (B) Protein levels of E-cadherin, N-cadherin, Vimentin, and ESRP1 in PC cells. (C,D) Invasion assays (left) and CCK-8 assays (right) in PaCa-2 (C) and AsPC-1 (D) cells. The experiments in (A,C,D) were repeated three times independently with similar results. *** p < 0.001.