Table 3.
Clinical Summaries of Patients with CMV Infections Who Developed Epilepsy or ASD.
| Patient No. | Sex/Labor | Age of CMV INF | Type of Infection | Antiviral Treatment | MR | Epilepsy/ Age of Dx |
ASD/ Age of Dx |
Last EEG Patterns/Age | Number of AED Uses | Seizure Control/Freq | Brain MRI |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CMV01 | F/P | 0 | Congenital | GCV | S | +/1 y | - | H yps/2 y | 4 | Unfavorable | WM |
| CMV02 | M/T | 0 | Congenital | GCV | M to S | +/1 y | +/3 y | Multi/5 y | 1 | Controlled | VM |
| CMV03 | M/T | 0 | Congenital | GCV | M | +/1 y | +/2 y | Multi/2 y | 1 | Controlled | HCP |
| CMV04 | F/T | 0 | Congenital | GCV | S | +/1 y | - | Multi/3 y | 1 | Controlled | HCP |
| CMV05 | M/T | 0 | E/P | - | - | +/2 y | - | Normal/9 y | 1 | Controlled | Normal |
| CMV06 | M/T | 1.5 y | Immunocompetent | - | - | +/2 y | - | Normal/8 y | 0 | Yearly | Normal |
| CMV07 | F/T | 1 y | Immunocompetent | - | M to S | +/1 y | - | Multi/2 y | 2 | Monthly | WM |
| CMV08 | F/P | 0 | Congenital | GCV | Mild | - | +/3 y | N/A | N/A | N/A | Normal |
| CMV09 | F/T | 2.1 y | Immunocompetent | - | - | - | +/3 y | N/A | N/A | N/A | Normal |
M, male; F, female; AED, Antiepileptic drug; E/P, Early postnatal; Dx, diagnosis; EEG, Electroencephalography; Freq, frequency; GCV, ganciclovir; +, present; -, not present; HCP, hydrocephalus; Hyps, hypsarrhythmia; INF, infection; MR, mental retardation; MRI, magnetic resonance imaging; M, moderate; Multi, multifocal spikes; N/A, not applicable; P, preterm; S, severe; T, term; VM, ventriculomegaly; WM, white matter lesions; y, years.