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. 2021 Oct 28;13(11):3846. doi: 10.3390/nu13113846

Figure 2.

Figure 2

Effect of time restricted feeding on hypothalamic clock gene mRNA expression and plasma corticosterone levels. (A) Arntl and (B) Reverbα mRNA expression in the mouse hypothalamus (n = 8 mice per time point per group) of control mice fed a TRF diet (Ctrl RF), jetlagged mice fed ad libitum (JL AL) and jetlagged mice fed a TRF diet (JL RF). (C) Plasma corticosterone levels (n = 4 mice per time point per group). The fitted cosine curve determined by cosinor analysis (period = 24 h) are shown in Ctrl RF, JL AL and JL RF mice. The dark phase is shaded grey. Statistics: Non-linear regression (Proc NLIN). ns = not significant. p values refer to probability values for the best fitting cosine curve.