Figure 10.

Description of the technology of conduction and delivery of drug-containing nanoparticles to the dental pulp. This technology exploits natural channels extending from the dentin to the pulp and magnetic force to deliver iron nanoparticles deep into the tooth structure. The technology was tested on rat molars and freshly extracted human teeth. It can be used to drug-load nanoparticles into the pulp or improve the bond strength of commercially available adhesive resins on the market in dentin (A) shows the surgery implantation of rhBMP-2 adsorbed MWCNT/CHI scaffolds into mouse subcutaneous muscular pocket. Optical microscope micrograph (B) shows regenerated bone tissue and a minor fraction of remaining MWCNT/CHI scaffold. Optical micrograph (C) shows a detail of regenerated bone tissue (collagen expressing cells, blue–green colored) after major disassembly of the MWCNT/CHI scaffold, surrounded by muscle tissue (pink colored). It is remarkable the well-limited interface between adjacent tissues (see black dash line). The remaining MWCNT/CHI scaffold (black colored) is pointed by black arrow [97].