Table 3.
Ventilation parameters at the predefined timepoints before and after the conversion from conventional ventilation to INTELLiVENT-ASV.
| Parameter | 2 h before Conversion | 1 h before Conversion | 1 h after Conversion | 2 h after Conversion | p Value |
|---|---|---|---|---|---|
| ∆P (cmH2O) | 13 (10–17) | 13 (10–17) | 11 (9–14) | 10 (8–14) | <0.001 |
| MP (J/min) | 21.5 (14.6–32.1) | 24.8 (19.4–31) | 18.8 (12.2–22) | 17.5 (12.2–21.1 | <0.001 |
| VT (mL) | 450 (400–530) | 473 (420–540) | 516 (455–568) | 520 (478–585) | 0.008 |
| VT (mL/kg PBW) | 6.3 (5.8–7.2) | 6.4 (5.9–7.1) | 7.1 (6.3–8.2) | 7.1 (6.5–7.8) | 0.008 |
| PEEP (cmH2O) | 10 (8–12) | 10 (8–12) | 10 (9–12) | 11 (9–12) | 0.5 |
| Pmax (cmH2O) | 26 (22–34) | 29 (22–35) | 26 (20–29) | 24 (19–28) | <0.001 |
| Pplat (cmH2O) | 24 (20–28) | 25 (21–28) | 23 (18–25) | 22 (19–25) | 0.002 |
| Pinsp (cmH2O) | 14 (9–18) | 14 (9–19) | 12 (7–15) | 11 (5–15) | <0.001 |
| RR (bpm) | 25 (20–30) | 28 (22–30) | 19 (16–21) | 18 (15–21) | <0.001 |
| Min. vol. (L/min) | 11 (8.7–12.6) | 11.8 (9.9–13.2) | 9.9 (8.5–11.3) | 9.8 (8.7–11.5) | 0.002 |
| FiO2 (%) | 60 (40–70) | 55 (45–65) | 44 (35–56) | 43 (32–53) | <0.001 |
| SpO2 (%) | 93 (92–96) | 94 (92–96) | 93 (92–95) | 93 (92–94) | 0.2 |
| etCO2 (kPa) | 6.1 (5.7–6.7) | 5.9 (5.4–6.4) | 5.9 (5.5–6.3) | 5.9 (5.3–6.2) | 0.5 |
| CRS (mL/cm H2O) | 35 (25–49) | 36 (26–53) | 47 (35–63) | 48 (35–63) | <0.001 |
Data are median (IQR). ∆P: driving pressure; MP: mechanical power; J/min: Joule per minute; VT: tidal volume; PBW: predicted body weight; cmH2O: centimeters of water; Pmax: maximum airway pressure; Pplat: plateau pressure; Pinsp: set inspiratory pressure; RR: respiratory rate; Min. vol.: minute volume; Bpm: beats per minute; FiO2: fraction of inspired oxygen; SpO2: pulse oximetry; etCO2: end-tidal carbon dioxide; kPa: kilopascal. CRS: compliance of the respiratory system.