Table 5.

Multivariable analysis of the C-section risk.

Multivariable Model	Variables Associated with C-Section	p-Value	aOR (95% CI)
C-section = COVID-19 symptoms + preterm delivery + interaction (COVID-19 symptoms and preterm delivery) + gestational age at diagnosis + pre-eclampsia + IVF	COVID-19 mild–moderate symptoms	0.523 a
	COVID-19 pneumonia	0.013 a	1.55 (1.09–2.18)
	Preterm delivery	0.003	2.44 (1.34–4.37)
	Interaction (COVID-19 mild–moderate symptoms and preterm delivery)	0.456
	Interaction (COVID-19 pneumonia and preterm delivery)	0.013	2.99 (1.27–7.25)
	Diagnosis in 2nd trimester	0.141 b
	Diagnosis in 3rd trimester	0.029 b	1.94 (1.10–3.64)
	Pre-eclampsia	<0.001	2.51 (1.55–4.04)
	IVF	<0.001	3.38 (2.10–5.44)

COVID-19 symptoms: 3 categories—asymptomatic, mild-moderate symptoms and pneumonia. Gestational age at diagnosis: 3 categories—1st trimester, 2nd trimester and 3rd trimester. Pre-eclampsia: moderate + severe. IVF: own oocyte + donor oocyte. ^a Compared to basal category—asymptomatic. ^b Compared to basal category—1st trimester.