Skip to main content
. 2021 Nov 22;14(11):1203. doi: 10.3390/ph14111203

Table 4.

Compound 4362.

No. Structure Assay Biological Data Reference
43 graphic file with name pharmaceuticals-14-01203-i043.jpg LPC assay IC50 = 43.6 nM [77]
44 graphic file with name pharmaceuticals-14-01203-i044.jpg LPC assay IC50 = 57.6 nM
45 graphic file with name pharmaceuticals-14-01203-i045.jpg LPC assay IC50 = 78.6 nM
46 graphic file with name pharmaceuticals-14-01203-i046.jpg FS-3 assay IC50 = 21 nM [78]
47 graphic file with name pharmaceuticals-14-01203-i047.jpg FS-3 assay IC50 = 9 nM [79]
48 graphic file with name pharmaceuticals-14-01203-i048.jpg FS-3 assay IC50 = 219 nM [80]
49 graphic file with name pharmaceuticals-14-01203-i049.jpg FS-3 assay IC50 = 218 nM
50 graphic file with name pharmaceuticals-14-01203-i050.jpg LPC assay IC50 = 472 nM [81]
51 graphic file with name pharmaceuticals-14-01203-i051.jpg LPC assay IC50 = 20 nM
52 graphic file with name pharmaceuticals-14-01203-i052.jpg LPC assay IC50 = 26 nM
53 graphic file with name pharmaceuticals-14-01203-i053.jpg LPC assay IC50 = 0.3 nM
54 graphic file with name pharmaceuticals-14-01203-i054.jpg LPC assay
Plasma assay
IC50 = 2 nM
IC50 = 9.7 nM
[82]
55 graphic file with name pharmaceuticals-14-01203-i055.jpg LPC assay
Plasma assay
IC50 = 1.1 nM
IC50 = 8.9 nM
56 graphic file with name pharmaceuticals-14-01203-i056.jpg LPC assay IC50 < 300 nM [83]
57 graphic file with name pharmaceuticals-14-01203-i057.jpg LPC assay IC50 = 81 nM
58 graphic file with name pharmaceuticals-14-01203-i058.jpg LPC assay IC50 = 473 nM [84]
59 graphic file with name pharmaceuticals-14-01203-i059.jpg LPC assay
Plasma assay
IC50 = 1 nM
IC50 = 14 nM
60 graphic file with name pharmaceuticals-14-01203-i060.jpg LPC assay(ewATX)
LPC assay(hATX)
IC50 = 87 nM
IC50 = 134 nM
[84]
61 graphic file with name pharmaceuticals-14-01203-i061.jpg LPC assay IC50 = 10.4 μM [23]
62 graphic file with name pharmaceuticals-14-01203-i062.jpg LPC assay IC50 = 8.8 μM