Table 4.

Input values of the independent parameters used for simulation.

Parameter	Values
eGFR at 6th month post-transplantation (base value for eGFR)	30–44 mL/min/1.73 m2
	45–59 mL/min/1.73 m2
Tac IPV	15–29.99%
	30–59.99%
CYP3A5 genotype (as mean C0/D during 6–12 months)	CYP3A5*1*/3 = 1.30 ± 0.54 ng/mL/mg
	CYP3A5*3*/3 = 1.92 ± 0.98 ng/mL/mg
Sex	Male = 1
	Female = 0
Acute rejection episode within the first post-transplantation year	Yes = 1
	No = 0