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Liver functions in HFD-induced MAFLD rats. N, normal control; HFD, high-fat diet; HFD + O, high-fat diet+orlistat 10 mg/kg/day (protective model); OB + O, obese + orlistat 10 mg/kg/day (therapeutic model); ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase. (A) ALT; (B) AST; (C) ALP. Data are expressed as mean ± SEM, n = 6/group. One-way ANOVA, followed by Tukey post-hoc test. a p < 0.05 vs. N group, b p < 0.05 vs. HFD group.
