Table 2.
Lee obesity index, body weight gain, food intake and calorie intake of rats in the experimental groups.
| N | HFD | HFD + O | OB + O | |
|---|---|---|---|---|
| Lee obesity index | 304.60 ± 1.43 | 334.20 ± 2.66 a | 310.00 ± 3.77 b | 314.50 ± 2.91 b |
| Initial body weight (g) | 218.20 ± 6.26 | 233.50 ± 7.53 | 226.60 ± 6.23 | 216.80 ± 13.82 |
| Final body weight (g) | 352.60 ± 13.68 | 474.00 ± 12.12 a | 403.5 ± 14.44 b | 390.80 ± 15.03 b |
| Body weight gain (g) | 93.17 ± 8.97 | 213.20 ± 12.95 a | 159.6 ± 6.92 a,b | 152.8 ± 8.31 a,b |
| Food intake (g/day) | 20.79 ± 0.56 | 21.22 ± 0.82 | 18.58 ±0.71 | 19.28 ± 0.66 |
| Calorie intake (kJ/day) | 276.50 ± 6.81 | 458.70 ± 17.72 a | 401.40 ± 15.39 a | 409.30 ± 18.64 a |
Data are presented as mean ± SEM, n = 6/group. N, normal control; HFD, high-fat diet; HFD + O, high-fat diet+orlistat 10 mg/kg/day (protective model); OB + O, obese+orlistat 10 mg/kg/day (therapeutic model). One-way ANOVA, followed by Tukey post-hoc test. a p < 0.05 vs. N group, b p < 0.05 vs. HFD group.