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. 2021 Nov 14;57(11):1244. doi: 10.3390/medicina57111244

Table 1.

Predisposing and precipitating factors for delirium.

Predisposing Factors
  • Older age;

  • Dementia or pre-existing cognitive impairment;

  • Previous delirium episodes;

  • Functional impairment;

  • Sensory impairment (e.g., vision and/or auditory disabilities);

  • Presence of comorbid medical illnesses;

  • Pre-existing neuropsychiatric disorders (e.g., depression, alcohol use disorder).

Precipitating Factors
  • Polypharmacotherapy (e.g., concomitant use of sedative-hypnotic drugs, diuretics, anticoagulants, antibiotics);

  • Use of physical restraints;

  • Use of bladder catheter;

  • Infections;

  • Major surgery;

  • Trauma or urgent admission to hospital;

  • Coma;

  • Metabolic abnormalities (e.g., abnormal serum sodium, glucose or potassium concentrations, hypoxemia, metabolic acidosis).