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. 2021 Nov 20;12(11):1834. doi: 10.3390/genes12111834

Table 4.

STAI and NEO Five Factor Inventory sten scores between healthy controls and all patients diagnosed with polysubstance use disorder comorbid with a depressive episode (PUD MDD) and all patients diagnosed with polysubstance use disorder comorbid with a depressive episode (PUD).

STAI/NEO Five Factor Inventory/ A:
PUD MDD
(n = 95)
B:
PUD
(n = 206)
C:
Control
(n = 301)
A/C:
Z
(p-Value)
B/C:
Z
(p-Value)
A/B:
Z
(p-Value)
STAI trait/scale 7.62 ± 2.25 6.87 ± 2.25 5.16 ± 2.17 7.062
(0.0000 *)
7.768
(0.0000 *)
3.665
(0.0002 *)
STAI state/scale 6.65 ± 2.21 5.54 ± 2.43 4.68 ± 2.14 8.207
(0.0000 *)
4.162
(0.0000 *)
2.754
(0.0059 *)
Neuroticism/scale 7.34 ± 2.00 6.45 ± 2.20 4.67 ± 2.01 9.264
(0.0000 *)
8.683
(0.0000 *)
3.094
(0.0020 *)
Extraversion/scale 5.44 ± 2.36 5.90 ± 2.01 6.37 ± 1.97 −3.640
(0.0003 *)
−2.412
(0.0147 *)
−1.837
(0.0602)
Openness/scale 5.46 ± 2.01 4.80 ± 2.00 4.53 ± 1.61 4.136
(0.0000 *)
1.401
(0.1545)
2.557
(0.0106 *)
Agreeability/scale 4.05 ± 1.99 4.41 ± 1.90 5.60 ± 2.09 −6.286
(0.0000 *)
−6.165
(0.0000 *)
−1.959
(0.0501 *)
Conscientiousness/scale 5.01 ± 2.14 5.85 ± 2.29 6.07 ± 2.15 −4.102
(0.0000 *)
−1.014
(0.3059)
−3.006
(0.0027 *)

p, statistical significance with Mann–Whitney U-test; n, number of subjects; M ± SD, mean ± standard deviation; * statistically significant differences.