Table 6.
Differences in DRD4 exon 3 (DRD4 Ex3), the NEO Five Factor Inventory, the STAI scale between healthy controls and PUD subjects.
| STAI/NEO Five Factor Inventory | DRD4 Ex3 | ANOVA | |||||||
|---|---|---|---|---|---|---|---|---|---|
| PUD (n = 206) |
Control (n = 301) |
s/s (n = 304) |
s/l (n = 169) |
l/l (n = 34) |
Factor | F (p-Value) | ɳ2 | Power (Alfa = 0.5) | |
| STAI trait/scale | 6.87 ± 2.25 | 5.16 ± 2.17 | 5.83 ± 2.49 | 6.00 ± 2.16 | 5.29 ± 2.14 | intercept | F1,501 = 1255.43 (p < 0.0001) * | 0.716 | 1.000 |
| PUD/control | F1,501 = 15.92 (p < 0.0001) * | 0.031 | 0.978 | ||||||
| DRD4 Ex3 | F2,501 = 0.98 (p = 0.375) | 0.004 | 0.221 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 1.52 (p = 0.219) | 0.006 | 0.324 | ||||||
| STAI state/scale | 5.54 ± 2.43 | 4.68 ± 2.14 | 4.99 ± 2.30 | 5.21 ± 2.27 | 4.50 ± 2.40 | intercept | F1,501 = 849.36 (p < 0.0001) * | 0.630 | 1.000 |
| PUD/control | F1,501 = 2.14 (p = 0.144) | 0.004 | 0.309 | ||||||
| DRD4 Ex3 | F2,501 = 1.41 (p = 0.245) | 0.006 | 0.303 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 1.21 (p = 0.299) | 0.005 | 0.264 | ||||||
| Neuroticism/scale | 6.45 ± 2.20 | 4.67 ± 2.01 | 5.46 ± 2.29 | 5.39 ± 2.16 | 4.67 ± 2.43 | intercept | F1,501 = 1196.67 (p < 0.0001) * | 0.705 | 1.000 |
| PUD/control | F1,501 = 27.48 (p < 0.0001) * | 0.052 | 0.999 | ||||||
| DRD4 Ex3 | F2,501 = 0.82 (p = 0.442) | 0.003 | 0.190 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 1.31 (p = 0.270) | 0.005 | 0.284 | ||||||
| Extraversion/scale | 5.90 ± 2.01 | 6.37 ± 1.97 | 6.15 ± 1.98 | 6.11 ± 2.03 | 6.76 ± 2.05 | intercept | F1,501 = 1803.32 (p < 0.0001) * | 0.782 | 1.000 |
| PUD/control | F1,501 = 0.73 (p = 0.391) | 0.001 | 0.137 | ||||||
| DRD4 Ex3 | F2,501 = 1.45 (p = 0.234) | 0.005 | 0.311 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 0.34 (p = 0.713) | 0.001 | 0.104 | ||||||
| Openness/scale | 4.80 ± 2.00 | 4.53 ± 1.61 | 4.51 ± 1.74 | 4.84 ± 1.82 | 4.85 ± 1.89 | intercept | F1,501 = 1335.71 (p < 0.0001) * | 0.727 | 1.000 |
| PUD/control | F1,501 = 3.99 (p = 0.046) | 0.008 | 0.514 | ||||||
| DRD4 Ex3 | F2,501 = 2.61 (p = 0.0740) | 0.010 | 0.520 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 0.99 (p = 0.372) | 0.003 | 0.222 | ||||||
| Agreeability/scale | 4.41 ± 1.90 | 5.60 ± 2.09 | 5.09 ± 2.12 | 5.22 ± 2.00 | 4.82 ± 2.25 | intercept | F1,501 = 993.33 (p < 0.0001) * | 0.665 | 1.000 |
| PUD/control | F1,501 = 33.04 (p < 0.0001) * | 0.061 | 0.999 | ||||||
| DRD4 Ex3 | F2,501 = 2.95 (p = 0.053) | 0.012 | 0.574 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 2.30 (p = 0.101) | 0.009 | 0.468 | ||||||
| Conscientiousness/scale | 5.85 ± 2.29 | 6.07 ± 2.15 | 5.93 ± 2.27 | 6.01 ± 2.14 | 6.26 ± 1.94 | intercept | F1,501 = 1357.97 (p < 0.0001) * | 0.730 | 1.000 |
| PUD/control | F1,501 = 0.002 (p = 0.961) | 0.00001 | 0.050 | ||||||
| DRD4 Ex3 | F2,501 = 0.53 (p = 0.587) | 0.002 | 0.138 | ||||||
| PUD/control x DRD4 Ex3 | F2,501 = 0.31 (p = 0.729) | 0.001 | 0.100 | ||||||
* Significant result.