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. 2021 Nov 20;12(11):1834. doi: 10.3390/genes12111834

Table 7.

Post hoc analysis of interactions between patients with polysubstance use disorder comorbid with a depressive episode (PUD MDD)/control and DRD4 exon 3 (DRD4 Ex3) and the NEO FFI Extraversion/Conscientiousness Scale.

DRD4 Ex3 and NEO FFI Extraversion Scale
{1}
M = 4.57
{2}
M = 5.71
{3}
M = 9.00
{4}
M = 6.28
{5}
M = 6.37
{6}
M = 6.73
PUD MDD DRD4 Ex3 s/l {1} 0.0145 * 0.0033 * 0.0001 * <0.0000 * 0.0001 *
PUD MDD DRD4 Ex3 s/s {2} 0.0261 * 0.0905 0.0290 * 0.0339 *
PUD MDD DRD4 Ex3 l/l {3} 0.0633 0.0720 0.1319
control DRD4 Ex3 s/l {4} 0.7060 0.3143
control DRD4 Ex3 s/s {5} 0.4060
control DRD4 Ex3 l/l {6}
DRD4 Ex3 and NEO FFI Conscientiousness Scale
{1}
M = 4.39
{2}
M = 5.14
{3}
M = 9.50
{4}
M = 6.13
{5}
M = 6.04
{6}
M = 6.15
PUD MDD DRD4 Ex3 s/l {1} 0.1210 0.0011 * 0.0002 * 0.0002 * 0.0025 *
PUD MDD DRD4 Ex3 s/s {2} 0.0045 * 0.0041 * 0.0042 * 0.0419 *
PUD MDD DRD4 Ex3 l/l {3} 0.0271 * 0.0226 * 0.0325 *
control DRD4 Ex3 s/l {4} 0.7281 0.9640
control DRD4 Ex3 s/s {5} 0.7980
control DRD4 Ex3 l/l {6}

* Statistically significant differences; M, mean.