Source	Search strategy	Hits retrieved
ALOIS (Cochrane Dementia and Cognitive Improvement Group Specialised Regsiter, searched via the Cochrane Register of Studies) [Date of most recent search: 16 September 2020]	Deliri* OR DEL [studies that are about delirium trestment or prevention are coded DEL in ALOIS]	June 2019: 240 Jan 2020: 106 Sep 2020: 67
CENTRAL (the Cochrane Library) http://crso.cochrane.org/SearchSimple.php [Date of most recent search: 16 September 2020]	#1 MESH DESCRIPTOR Delirium EXPLODE ALL TREES #2 deliri*:TI,AB,KY #3 ("acute confusion*" ):TI,AB,KY #4 ("acute confusion*" ):TI,AB,KY #5 ("acute organic psychosyndrome" ):TI,AB,KY #6 ("acute brain syndrome" ):TI,AB,KY #7 ("metabolic encephalopathy" ):TI,AB,KY #8 ("acute psycho‐organic syndrome" ):TI,AB,KY #9 ("clouded state" ):TI,AB,KY #10 ("clouding of consciousness" ):TI,AB,KY #11 ("exogenous psychosis" ):TI,AB,KY #12 ("toxic psychosis" ):TI,AB,KY #13 ("toxic confusion" ):TI,AB,KY #14 obnubilat*:TI,AB,KY #15 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 #16 MESH DESCRIPTOR Hospitals EXPLODE ALL TREES #17 MESH DESCRIPTOR Patient Care EXPLODE ALL TREES #18 MESH DESCRIPTOR Inpatients EXPLODE ALL TREES #19 Hospital*:TI,AB,KY #20 "In‐patient":TI,AB,KY #21 Ward*:TI,AB,KY #22 Inpatient*:TI,AB,KY #23 #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 #24 #15 AND #23	June 2019: 1642 Jan 2020: 531 Sep 2020:157
MEDLINE In‐process and other non‐indexed citations and MEDLINE 1950‐present (Ovid SP) [Date of most recent search: 16 September 2020]	1. Delirium/ 2. deliri*.mp. 3. "acute confusion*".ti,ab. 4. "acute organic psychosyndrome".ti,ab. 5. "acute brain syndrome".ti,ab. 6. "metabolic encephalopathy".ti,ab. 7. "acute psycho‐organic syndrome".ti,ab. 8. "clouded state".ti,ab. 9. "clouding of consciousness".ti,ab. 10. "exogenous psychosis".ti,ab. 11. "toxic psychosis".ti,ab. 12. "toxic confusion".ti,ab. 13. Delirium, Dementia, Amnestic, Cognitive Disorders/su [Surgery] 14. obnubilat*.ti,ab. 15. or/1‐14 16. Hospitals/ 17. Inpatients/ 18. Patient Care/ 19. Hospital*.ti,ab. 20. "In‐patient".ti,ab. 21. Ward*.ti,ab. 22. Inpatient*.ti,ab. 23. 16 or 17 or 18 or 19 or 20 or 21 or 22 24. randomized controlled trial.pt. 25. controlled clinical trial.pt. 26. randomi?ed.ab. 27. placebo.ab. 28. drug therapy.fs. 29. randomly.ab. 30. trial.ab. 31. groups.ab. 32. 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 33. (animals not (humans and animals)).sh. 34. 32 not 33 35. 15 and 23 and 34	June 2019: 1873 Jan 2020: 216 Sep 2020: 136
EMBASE (Ovid SP) 1974 to 15 January 2020 [Date of most recent search: 16 September 2020]	1. Delirium/ 2. deliri*.mp. 3. "acute confusion*".ti,ab. 4. "acute organic psychosyndrome".ti,ab. 5. "acute brain syndrome".ti,ab. 6. "metabolic encephalopathy".ti,ab. 7. "acute psycho‐organic syndrome".ti,ab. 8. "clouded state".ti,ab. 9. "clouding of consciousness".ti,ab. 10. "exogenous psychosis".ti,ab. 11. "toxic psychosis".ti,ab. 12. "toxic confusion".ti,ab. 13. Delirium, Dementia, Amnestic, Cognitive Disorders/su [Surgery] 14. obnubilat*.ti,ab. 15. or/1‐14 16. Hospitals/ 17. Inpatients/ 18. Patient Care/ 19. Hospital*.ti,ab. 20. "In‐patient".ti,ab. 21. Ward*.ti,ab. 22. Inpatient*.ti,ab. 23. 16 or 17 or 18 or 19 or 20 or 21 or 22 24. randomized controlled trial.pt. 25. controlled clinical trial.pt. 26. randomi?ed.ab. 27. placebo.ab. 28. drug therapy.fs. 29. randomly.ab. 30. trial.ab. 31. groups.ab. 32. 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 33. (animals not (humans and animals)).sh. 34. 32 not 33 35. 15 and 23 and 34	June 2019: 6907 Jan 2020: 1117 Sep 2020:748
PsycINFO (Ovid SP) [Date of most recent search: 16 September 2020]	1 Delirium/ 2 deliri*.mp. 3 "acute confusion*".ti,ab. 4 "acute organic psychosyndrome".ti,ab. 5 "acute brain syndrome".ti,ab. 6 "metabolic encephalopathy".ti,ab. 7 "acute psycho‐organic syndrome".ti,ab. 8 "clouded state".ti,ab. 9 "clouding of consciousness".ti,ab. 10 "exogenous psychosis".ti,ab. 11 "toxic psychosis".ti,ab. 12 "toxic confusion".ti,ab. 13 obnubilat*.ti,ab. 14 or/1‐13 15 exp HOSPITALS/ 16 exp Hospitalized Patients/ 17 Hospital*.ti,ab. 18 "In‐patient".ti,ab. 19 Ward*.ti,ab. 20 Inpatient*.ti,ab. 21 or/15‐20 22 exp Clinical Trials/ 23 randomly.ab. 24 randomi?ed.ti,ab. 25 placebo.ti,ab. 26 groups.ab. 27 "double‐blind*".ti,ab. 28 "single‐blind*".ti,ab. 29 RCT.ti,ab. 30 or/22‐29 31 14 and 21 and 30 32 from 31 keep 1‐288	June 2019: 332 Jan 2020: 21 Sep 2020:365
CINAHL (EBSCOhost) [Date of most recent search: 16 September 2020]	1 deliri* 2 "acute psycho‐organic syndrome" or "clouded state" or "clouding of consciousness" or "exogenous psychosis" or "toxic psychosis" or "toxic confusion" 3 "acute brain confusion" or "acute brain failure" or "acute organic psychosyndrome" or "acute brain syndrome" or "metabolic encephalopathy" 4 "Delirium"/ 5 (S1 OR S2 OR S3 OR S4) 6 (MH "Hospitals+") 7 (MH "Inpatients") 8 TX Hospital* 9 TX "In‐patient" 10 Ward* 11 Inpatient* 12 (MH "Patient Care") 13 (S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12) 14 MH "Clinical Trials" 15 TX trial 16 TX "single‐blind*" 17 TX "double‐blind*" 18 TX "treatment as usual" 19 TX randomly 20 S14 OR S15 OR S16 OR S17 OR S18 OR S19 21 S5 AND S13 AND S20	June 2019: 1,498 Jan 2020: 461 Sep 2020: 144
ISI Web of Science – core collection [Date of most recent search: 16 September 2020]	TOPIC:(deliri* OR "acute confusion*" OR "acute organic psychosyndrome" OR "acute brain syndrome" OR "metabolic encephalopathy" OR "acute psycho‐organic syndrome" OR "clouded state" OR "clouding of consciousness" OR "exogenous psychosis" OR "toxic psychosis" OR "toxic confusion" OR obnubilat*)ANDTOPIC:(hospital* OR Inpatient* OR In‐patient* OR ward OR "In patient*")AND TOPIC:(randomly OR randomised OR randomized OR "random allocat*" OR RCT OR CCT OR "double blind*" OR "single blind*" OR "double blind*" OR "single blind*" OR trial)	June 2019: 1612 Jan 2020: 186 Sep 2020: 321
LILACS (BIREME) [Date of most recent search: 16 September 2020]	deliri$ OR delirio OR loucura [Words]and hospital$ OR inpatient$ [Words]	June 2019: 417 Jan 2020: 13 Sep 2020: 9
ClinicalTrials.gov (www.clinicaltrials.gov) [Date of most recent search: 16 September 2020]	HOSPITAL OR INPATIENT | delirium OR toxic psychosis OR toxic confusion	June 2019: 540 Jan 2020: 97 Sep 2020: 68
ICTRP [Date of most recent search: 15 January 2020. Database not available 16 September 2020]	HOSPITAL OR INPATIENT | delirium OR toxic psychosis OR toxic confusion	June 2019: 89 Jan 2020: 18
TOTAL before de‐duplication		June 2019: 15,150 Jan 2020: 2766 Sep 2020: 2015
TOTAL after de‐duplication		June 2019: 10,810 Jan 2020: 2246 Sep 2020:1682