Humeidan 2015.

Study name	Perioperative cognitivepProtection ‐ Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)
Methods	Randomised clinical trial
Participants	322 patients (≥60 years) who underwent non‐cardiac/non‐neurological surgery with expected hospital stay of at least 72 hours.
Interventions	Group 1: cognitive exercises consisting of a series of computer games focusing on five categories: memory, speed, attention, flexibility and problem‐solving Group 2: standard care
Outcomes	Primary outcome(s): reduction in the incidence of PostOperative Delirium (%) [ Time Frame: Postoperative period (Day 0 through Day 7 or discharge, whichever comes first)] as detected by the Confusion Assessment Method (CAM) / Memorial Delirium Assessment Scale (MDAS) Secondary outcome(s): Mini‐Mental State Examination, Self‐Administered Gerocognitive Examination, Geriatric Depression Scale, Charlson Comorbidity Index, Short Form 36 Health Survey, Confusion Assessment Method, Memorial Delirium Assessment Scale, Postoperative Quality of Recovery Scale
Starting date	July 2015
Contact information	Michelle L Humeidan, michelle.humeidan@osumc.edu Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, Ohio
Notes	ClinicalTrials.gov Identifier: NCT02230605 Status: completed