Wong 2018.

Study name	The prevention of delirium in elderly with obstructive sleep apnea (PODESA) study: protocol for a multi‐centre prospective randomized, controlled trial
Methods	Randomised controlled trial
Participants	304 patients (≥60 years) scheduled for elective hip or knee replacement surgery at least 4 working days after the preadmission clinic visit
Interventions	Group 1: auto‐titrating Continuous Positive Airway Pressure (CPAP) treatment will be given on postoperative days 1, 2, and 3. Group 2: standard care
Outcomes	Primary outcome: incidence of postoperative delirium over 2 months Secondary outcome(s): length of hospital stay, time to ambulate (1 week to 2 months) perioperative complications at 10‐14 days
Starting date	24/03/2016
Contact information	Jean Wong, University Health Network, Toronto
Notes	ClinicalTrials.gov Identifier: NCT02954224 Status: Active, not recruiting Estimated completion date: 30/08/2020

CAM: Confusion Assessment Method; SF‐36: Short Form survey; STAI‐6: State‐Trait Anxiety Inventory;TNFa: tumour necrosis factor alpha; VAS: visual analogue scale.