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. 2021 Nov 16;11(11):1237. doi: 10.3390/life11111237

Figure 4.

Figure 4

TSLP transcriptional regulator AP1 is up-regulated and active in EGFR∆ep mice. (A–F) Immunofluorescence of 5-µm back-skin cryo-sections of 20-day-old (P20) WT and EGFR∆ep mice for AP-1 members (JunB (A), c-Jun (B), c-Fos (C), Fra2 (D), JunD (E), and phospho c-Jun (F)). The basal membrane, separating epidermis (upper part) from dermis (lower part), was visualized with Integrin b4 when indicated. Nuclei were visualized with Hoechst. Colours are as indicated next to the pictures. Data are representative of three independent mice per genotype. The insets show an enlarged view of the framed epidermal areas with KCs. Scale bars, 50 µm. Mice were analysed 20 days after birth (P20).