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. 2021 Nov 17;10(11):3203. doi: 10.3390/cells10113203

Figure 9.

Figure 9

The If current is upregulated in human terminal heart failure due to ischemic (ICM) and dilated cardiomyopathy (DCM). (A) Representative original If current recordings from a control (donor heart), an explanted ICM and DCM heart, during membrane hyperpolarization to increasing negative potentials from −60 to −130 mV. (B) Summary graph of If density at −120 mV in control, ICM and DCM hearts; ** p < 0.001 vs. control, # p < 0.01 vs. ICM. (C) The average If densities measured in individual control, ICM and DCM hearts [165]; * p < 0.01 vs. control, # p < 0.05 vs. ICM. Open squares represent the corresponding mean for each group.