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. 2021 Nov 13;11(11):1196. doi: 10.3390/jpm11111196

Table 1.

Classification of vaccines during pregnancy according to their safety profiles and recommendations in vaccination programs or special circumstances and settings.

Category of Vaccination
during Pregnancy
Types and Comments Active Immunization Products Abbrv.
Routine vaccinations Inactivated vaccines approved in European countries Inactivated influenza vaccines IIV3, IIV4
Tetanus, diphtheria, pertussis vaccine Tdap
Vaccinations in special circumstances and settings Different non-LAV types of vaccines, some with ongoing safety monitoring COVID-19 vaccine
Hepatitis A and B vaccines HepA, HepB
Pneumococcal vaccines PPSV23, PCV13
Meningococcal vaccines MenACWY
Haemophilus influenzae type b vaccine Hib
Inactivated polio vaccine IPV
Inactivated rabies vaccine RAB
Inactivated tick encephalitis vaccine TBE
Inactive typhoid vaccine Ty21a
Human papillomavirus vaccine * HPV
Contraindicated vaccinations LAV vaccines contraindicated during pregnancy Measles, mumps, and rubella vaccine MMR
Varicella vaccine VAR
Live-attenuated influenza vaccine LAIV
Live zoster (shingles) vaccine ZVL
Yellow fever and dengue vaccines YF, DEN

Legend: Abbrv. = abbreviation; * HPV vaccine is generally not recommended during pregnancy due to a lack of data regarding its safety and efficacy in this population; IIV3, IIV4 = inactivated influenza vaccines trivalent, tetravalent; Tdap = tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis; COVID-19 = coronavirus disease 2019; Hib = Haemophilus influenzae type b vaccine; HPV = human papillomavirus; MMR = measles, mumps, and rubella; LAV = live-attenuated virus.