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. 2021 Nov 14;13(11):4070. doi: 10.3390/nu13114070

Figure 2.

Figure 2

The effect of Icariin on Doxo-treated H9c2 cell viability. (A). Incubation of H9c2 cells with Icariin (Ica) alone, at increasing concentrations, did not result in a reduction of cell viability compared to the Ctrl group. (B). Pretreatment with increasing concentrations of Ica for 3 h protects cardiomyoblasts from Doxo induced toxicity. Data are expressed as mean ± SEM *** p < 0.001 vs. Ctrl; °°° p < 0.001 vs. Ica 1 μM; ^^ p < 0.01 vs. Ica 5 μM; ## p < 0.01 vs. Doxo; ### p < 0.001 vs. Doxo; Mann Whitney test (n = 8). Data is from three different independent experiments.