Doxo | doxorubicin |
ROS | reactive oxygen species |
Ica | icariin |
CVDs | cardiovascular diseases |
HF | heart failure |
mPTP | mitochondrial permeability transition pore |
ETC | electron transport chain |
CypD | cyclophilin d |
Ca2+ | calcium |
RNS | reactive nitrogen species |
O2− | anion superoxide |
NO | nitric oxide |
I/R | ischemia-reperfusion |
sGC | soluble guanylyl cyclase |
cGMP | cyclic gmp |
PDE5a | phosphodiesterase 5a |