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. 2021 Nov 12;11(11):2096. doi: 10.3390/diagnostics11112096

Table 4.

Cancer sites and stages across study periods in 2020.

Period (2020)
Pre-COVID COVID-Impacted De-Escalation Second Wave 26 February–30 December
Total, n (%) 38/176 (21.59) 20/126 (15.87) 29/169 (17.16) 93/504 (18.45) 142/799 (17.77)
Mean (weekly) ± SD 4.75 ± 1.28 2.22 ± 1.48 3.22 ± 1.72 3.58 ± 1.30 3.23 ± 1.49
Percent reduction (95% CI) −2.59 (−24.09–18.92) 54.07 (32.45–75.70) 30.03 (−1.89–61.94) 17.55 (2.63–32.47) 27.57 (15.91–39.23)
p-value 0.8631 0.0005 0.0439 0.0028 <0.0001
Primary site/stage III-IV, n (%)/(%)
Pancreatic 7 (18.42)/5 (71.43) 4 (20.00)/3 (75.00) 6 (20.70)/4 (66.67) 15 (16.13)/12 (80.00) 25 (17.61)/19 (76.00)
Colorectal 6 (15.79)/3 (50.00) 3 (15.00)/1 (33.33) 5 (17.24)/2 (40.00) 18 (19.35)/10 (55.56) 26 (18.31)/13 (50.00)
Hematological 6 (15.79)/(n.a.) 3 (15.00)/(n.a.) 4 (13.79)/(n.a.) 15 (16.13)/(n.a.) 22 (15.49)/(n.a.)
Lung 5 (13.16)/3 (60.00) 2 (10.00)/1 (50.00) 4 (13.79)/3 (75.00) 13 (13.98)/11 (84.62) 19 (13.38)/15 (78.95)
Upper gastrointestinal tract 3 (7.89)/2 (66.67) 1 (5.00)/1 (100.00) 2 (6.90)/1 (50.00) 6 (6.45)/6 (100.00) 9 (6.34)/8 (88.89)
Renal and bladder 2 (5.26)/1 (50.00) 1 (5.00)/0 (0.00) 2 (6.90)/1 (50.00) 4 (4.30)/1 (25.00) 7 (4.93)/2 (28.57)
Hepatobiliary 2 (5.26)/2 (100.00) 1 (5.00)/1 (100.00) 1 (3.45)/1 (100.00) 4 (4.30)/3 (75.00) 6 (4.23)5 (83.33)
Breast 2 (5.26)/1 (50.00) 2 (10.00)/2 (100.00) 2 (6.90)/2 (100.00) 7 (7.53)/5 (71.43) 11 (7.75)/9 (81.82)
Prostate 2 (5.26)/2 (100.00) 1 (5.00)/1 (100.00) 1 (3.45)/1 (100.00) 3 (3.23)/2 (66.67) 5 (3.52)/4 (80.00)
Gynecological 1 1 (2.63)/0 (0.00) 1 (5.00)/1 (100.00) 1 (3.45)/1 (100.00) 4 (4.30)/3 (75.00) 6 (4.23)/5 (83.33)
Cancer of unknown primary site 1 (2.63)/1 (100.00) 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 1 (1.08)/1 (100.00) 1 (0.70)/1 (100.00)
Sarcoma 1 (2.63)/1 (100.00) 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 2 (2.15)/1 (50.00) 2 (1.41)/1 (50.00)
Neuroendocrine tumor 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 1 (3.45)/1 (100.00) 0 (0.00)/(n.a.) 1 (0.70)/1 (100.00)
Malignant melanoma 0 (0.00)/(n.a.) 1 (5.00)/1 (100.00) 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 1 (0.70)/1 (100.00)
Mesothelioma 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 0 (0.00)/(n.a.) 1 (1.08)/1 (100.00) 1 (0.70)1 (100.00)
Stage III-IV 2, total n (%) 21/32 (65.63) 12/17 (70.59) 17/25 (68.00) 56/78 (71.79) 85/120 (70.83)

1 Ovarian, endometrial, and cervical cancer; 2 Excluding hematological malignancies.