Table 1.
Antibacterial activity of compound 62520 against clinical carbapenem-resistant A. baumannii isolates.
| Sequence Type | MIC (μg/mL) | IC50 (μg/mL) * |
|---|---|---|
| ST191 (n = 5) | >32 | 8.62 ± 3.46 |
| ST208 (n = 5) | >32 | 7.23 ± 2.41 |
| ST369 (n = 5) | >32 | 6.58 ± 2.63 |
| ST451 (n = 5) | >32 | 8.30 ± 2.08 |
| ST784 (n = 5) | >32 | 6.35 ± 3.05 |
* The half-maximal inhibitory concentration of compounds (IC50) was the compound 62520 concentration showing 50% of the maximal inhibition. This was calculated as follows: relative maximal inhibition% − 50% × (relative maximal inhibition% − relative minimal inhibition%).