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. 2021 Oct 28;9(11):1249. doi: 10.3390/vaccines9111249

Table 1.

Virus production and titration methods.

Virus and Formulation Type Figures Viral Production Process Starting Infectivity Titer (IU/mL) Starting Viral Particle Titer (VP/mL) VP Assay Method
ChAdOx1 RVF, liquid Figure 1A, Figure 2A,B and Figure 3A–D No chromatography, inhouse 1.5 × 109 2.1 × 1011 qPCR, inhouse [24]
ChAdOx2 RabG, liquid Figure 1B and Figure 2A,B With chromatography 2.2 × 109 2.2 × 1011 Spectrophotometry [25]
ChAdOx1 RVF, liquid Figure 2C With chromatography 2.3 × 109 Not performed Not performed
ChAdOx2 RabG, liquid Figure 2C With chromatography 2.20 × 109 2.2 × 1011 Spectrophotometry [25]
ChAdOx1 RVF for lyophilisation Figure 4A,C,D No chromatography, advent 3.0 × 109 1.0 × 1011 Proprietary qPCR
ChAdOx2 RabG for lyophilisation Figure 4B With chromatography 1.8 × 109 IU/mL 1.3 × 1011 Spectrophotometry [25]